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Genetic Testing

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Genetic testing is a type of medical test that identifies changes in chromosomes, genes, or proteins. The results of a genetic test can confirm or rule out a suspected genetic condition or help determine a person’s chance of developing or passing on a genetic disorder. More than 1,000 genetic tests are currently in use, and more are being developed.

Several methods can be used for genetic testing:
  • Molecular genetic tests (or gene tests) study single genes or short lengths of DNA to identify variations or mutations that lead to a genetic disorder.

  • Chromosomal genetic tests analyze whole chromosomes or long lengths of DNA to see if there are large genetic changes, such as an extra copy of a chromosome, that cause a genetic condition.

  • Biochemical genetic tests study the amount or activity level of proteins; abnormalities in either can indicate changes to the DNA that result in a genetic disorder. 

Genetic testing has benefits as well as limitations and risks, the decision about whether to be tested is a personal and complex one. 

[1] NIH, Genetic Home Reference, "What is genetic testing" (March 10, 2014).

Alerts

FDA Consumer Information: cobas® HPV Test - P100020/S008 
05/01/2014

FDA approves HPV test for Primary Cervical Cancer Screening
04/24/2014

FDA Panel Approves Cologuard DNA Test for Colorectal Cancer
04/01/2014

Roche's DNA Test May Replace Pap Smears
03/13/2104

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