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Australian Study Confirms HPV Vaccine is Working; Call for Higher Vaccination Rates in the U.S.

3/28/2014

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The results of a longterm Australian study recently published in the British Medical Journal showed a clear association between human papillomavirus (HPV) vaccination and significantly reduced risk of developing  cervical abnormalities.  Girls and young women who received all three recommended does of the vaccine had a 46% reduction in the risk of high-grade cervical lesions and a 34% reduction in the risk of all other cervical abnormalities.  

In the U.S., every year 14 million people are newly infected and 26,000 cancers attributable to HPV are diagnosed. Four leading U.S. medical organizations - the American Academy of Family Physicians (AAFP), the American Academy of Pediatrics (AAP), the American College of Physicians (ACP), and the American College of Obstetricians and Gynecologists (ACOG) - together with the Immunization Coalition and the Centers for Disease Control and Prevention, have issued a joint statement calling on U.S. physicians to strongly recommend the vaccination to their patients, especially adolescent girls and boys.  Currently only 30% of eligible girls and young women in the U.S. have received the HPV vaccination.

[1] Crowe, E. "Effectiveness of quadrivalent human papillomavirus vaccine for the prevention of cervical abnormalities: case-control study nested within a population based screening programme in Australia" BMJ 2014; 348:g1458.

[2] AAFP Press Release: "Leading Medical and Public Health Organizations Join Efforts Urging Physicians to Strongly Recommend Human Papillomavirus (HPV) Vaccination"  (Feb. 12, 2014). 

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